Product Opportunity Evaluation and Maximisation (POEM)

Product Opportunity Evaluation and Maximisation (POEM)

A new therapeutic about to enter the clinic with a range of possible different indications and disease populations needed to determine the best development path and target product profile, as well as explore the risk/reward balance between the various development options and pricing implications.

CASE STUDY 1

SITUATION
A new therapeutic about to enter the clinic with a range of possible different indications and disease populations needed to determine the best development path and target product profile, as well as explore the risk/reward balance between the various development options and pricing implications.
SERVICE
Built and executed a clear process to brainstorm and prioritise disease populations, identify key decision criteria, and test the sensitivity of those disease population options to the decision criteria, before hybridising the most preferred populations to test the risk/return trade-offs.
RESULT
A clear development path with an early proof of concept in a niche population that built confidence so that an acceptable risk/return ratio was achieved in a broader disease population.

CASE STUDY 2

SITUATION
A European pharmaceutical organisation was interested in acquiring a company based in the UK.
SERVICE
– Perform commercial due diligence on the portfolio of products
– Provide sales and profit forecasts to validate the target company’s projections, and provide justifications of forecast differences
– Comment on the likely robustness of the forecasts given the competition, pricing, reimbursement and regulatory environment
RESULT
– Highlighted areas of high commercial uncertainty and major differences between the forecasts and the target company’s forecasts
– Confirmed overall the commercial viability of the target’s portfolio over the projected period
– Provided independent decision making support for the successful acquisition

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Claude Houet
Director

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